John Mccain
john-mccain.jpg
http://blog.tmcnet.com/blog/tom-keating/images/john-mccain.jpg

Biography
John Mccain was born August 29, 1936 in the Panama Canal zone. His parents are Admiral John McCain and Roberta McCain. He grew up to lead a very successful in politics from being a U.S. representative to a U.S. Senator to the 2008 republican presidential canidate. He has a family that consists of his wife (Cindy), 4 sons (Douglas, Andrew, John IV, and James) and 3 daughters (Sidney, Meghan, and Bridget). Throughout his childhood, John was always suffereing from very bad sunburns. This was the origin of his diagnosed melanoma (skin cancer) in 1993 and again 2000.
http://www.biography.com/articles/John-McCain-9542249?part=2
Melanoma (Skin Cancer)
Melanoma is a disease in which malignant (cancer) cells form in the skin cells called melanocytes (cells that color the skin).
  • Symptoms
    • You can usually spot melanoma early by inspecting your skin every once and a while. The most common sympton of melanoma is when new or existing moles start to change. You can check any melanoma_4.jpgabnormal looking moles with the ABCD method.
      • Asymmetry: The shape of one half does not match the other.
      • Border: The edges are often ragged, notched, blurred, or irregular in outline; the pigment may spread into the surrounding skin.
      • Color: The color is uneven. Shades of black, brown, and tan may be present. Areas of white, grey, red, pink, or blue also may be seen.
      • Diameter: There is a change in size, usually an increase. Melanomas are usually larger than the eraser of a pencil (1/4 inch or 5 millimeters)
  • Risk Factors
    • There are many risk factor for melanoma. Long exposure to sunlight that results in sunburn along with sunlamps and tanning booths have been directly related to melanoma. Other risk factors include your family and personal history. Chances are, if you'd had it once, then its gonna happen again. Also, having very pale skin and freckles can higher your risk for melanoma.
      ginger.jpg
      Pale and Freckles http://www.examiner.com/images/blog/EXID15166/images/ginger.jpg
      tanning.jpg
      http://girlmeetslife.com/wp-content/uploads/2010/05/5.11.10.3.jpg


  • Epidemiology

Incidence Rates by Race||~ Race/Ethnicity ||~ Male ||~ Female ||
All Races
26.7 per 100,000 men
16.7 per 100,000 women
White
30.9 per 100,000 men
19.7 per 100,000 women
Black
1.2 per 100,000 men
0.9 per 100,000 women
Asian/Pacific Islander
1.6 per 100,000 men
1.3 per 100,000 women
American Indian/Alaska Native
3.9 per 100,000 men
3.7 per 100,000 women
Hispanic
4.0 per 100,000 men
3.9 per 100,000 women
melanoma.gif
http://www.advancedmcode.org/home/wp-content/uploads/2011/04/melanoma.gif
This table shows the trends that are seen between race/ethnicity with incidents of melanoma.
Death Rates by Race||~ Race/Ethnicity ||~ Male ||~ Female ||
All Races
4.0 per 100,000 men
1.7 per 100,000 women
White
4.5 per 100,000 men
2.0 per 100,000 women
Black
0.5 per 100,000 men
0.4 per 100,000 women
Asian/Pacific Islander
0.4 per 100,000 men
0.3 per 100,000 women
American Indian/Alaska Native a
1.6 per 100,000 men
0.8 per 100,000 women
Hispanic b
1.0 per 100,000 men
0.6 per 100,000 women
This table shows the trends that are seen between race/ethnicity with death rates of melanoma.

Stage Distribution and 5-year Relative Survival by Stage at Diagnosis for
2001-2007, All Races, Both Sexes ||~ Stage at Diagnosis ||~ Stage
Distribution (%) ||~ 5-year Relative Survival (%) ||
Localized (confined to primary site)
84
98.1
Regional (spread to regional lymphnodes)
8
61.4
Distant (cancer has metastasized)
4
15.3
Unknown (unstaged)
4
74.6
This table shows the % of patients that have at least a 5 year survival rate from certain stages of melanoma.

  • Treatments
    • There are four standard treatments for melanoma. There is your basic surgery where surgeons will cut away at the cancerous area on your skin until they can find no more trace of the melanoma. Then, there is chemotherapy where they trat the melanoma with chemicals in order to kill the cancerous cells. Theres also radiation therapy which is basically the same thing except they treat the melanoma with radiation instead of chemicals. Biological therapy is fourth choice for treatment. This is where doctors will try to give you meds to boost your immune system to fight off the cancerous cells.
    • Clinical Trials
      • Chemoimmunotherapy is the use of anticancer drugs combined with biologic therapy to boost the immune system to kill cancer cells.
      • Vaccine Therapy is the use of vaccines to help your immune system identify cancer cells so that it is easier to fight off.
      • Targeted Therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells without harming normal cells.
  • Hopes for Victims
    • The chances of beating this disease are in the victims favor for most cases. As long as the disease is caught early the melanom can be considered easily beatable. If you look at the 2nd table in the epidemiology section, it shows that 98% of cases caught early have at least a 5 year survival rate which is very good when it comes to cancer. Also, there is the differences in the two tables between the trends of race/ethnicity and melanoma. The death rate is much lower than the incident rate showing that a good amount of people beat the disease. Hope is very strong for those patients who catch their melanoma early which can be very easy using the ABCD method.
      mccain.jpg
      http://www.myhousecallmd.com/wp-content/uploads/2010/07/y7a-mccn-n4s2.jpg
http://www.cancer.gov/cancertopics/types/melanoma
http://www.medicinenet.com/melanoma/page4.htm

Conclusion
John McCain has had one major enemy in his lifetime, the sun. Throughout his lifetime he has had numerous occasions in which he has suffered severe sunburns. These severe sunburns would most likely be considered the factor that has caused his melanoma in 1993 and again in 2000. Luckily, he survived these cases from the most common treatment, basic surgery which lasted 9 hours. The doctors slowly cut away at the cancerous skin cells over and over again. Each time they would examine the cells until they found no trace of the cancer left. It saved his life and McCain is now, for the most part, completely healthy. From that experience he has turned a new leaf. He is now a sunscreen fanatic and is constantly lathering on himself and his family. Not only that but, he has become a big supporter of one of the major skin cancer foundations in the world, the Shade Foundation of America.
http://www.newsweek.com/2008/02/19/surviving-skin-cancer.html
http://www.riskworld.com/PressRel/2001/01q3/PR01a027.htm
http://www.shadefoundation.org/friends-of-shade.php